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Fifth Edition

Edited by Dale Purves, Edited by George J. Augustine, Edited by David Fitzpatrick, Edited by William C. Hall, Edited by Anthony-Samuel LaMantia, and Edited by Leonard E. White

April 2018

ISBN: 9781605357416

858 pages

In Stock

Price: £54.99

A comprehensive, clearly written textbook that introduces the field of neuroscience from the abstract to the everyday.



Published by Sinauer Associates, an imprint of Oxford University Press.

This comprehensive textbook has been created primarily for medical, premedical, and undergraduate students. In a single concise and approachable volume, the text guides students through the challenges and excitement of this rapidly changing field.

  • In addition to new figures, all of the art has been modified with a new colour palette and digital enhancements
  • All chapters have been updated to reflect current research; new literature citations have been added, as well as new experimental content. Substantial revisions have been made to: Chapter 4, Ion Channels and Transporters; Chapter 6, Neurotransmitters and Their Receptors; and Chapter 8, Synaptic Plasticity; all chapters in Unit IV, The Changing Brain; and all chapters in Unit V, Complex Brain Functions.
  • A free Sylvius 4 download is included with every book
  • An appendix presents an illustated narrative of human neuroanatomy plus annotated atlas plates present brain sections from Sylvius

Table of Contents

    1: Studying the Nervous System
    UNIT I: Neural Signaling
    2: Electrical Signals of Nerve Cells
    3: Voltage-Dependent Membrane Permeability
    4: Ion Channels and Transporters
    5: Synaptic Transmission
    6: Neurotransmitters and Their Receptors
    7: Molecular Signaling within Neurons
    8: Synaptic Plasticity
    UNIT II: Sensation and Sensory Processing
    9: The Somatic Sensory System: Touch and Proprioception
    10: Pain
    11: Vision: The Eye
    12: Central Visual Pathways
    13: The Auditory System
    14: The Vestibular System
    15: The Chemical Senses
    UNIT III: Movement and Its Central Control
    16: Lower Motor Neuron Circuits and Motor Control
    17: Upper Motor Neuron Control of the Brainstem and Spinal Cord
    18: Modulation of Movement by the Basal Ganglia
    19: Modulation of Movement by the Cerebellum
    20: Eye Movements and Sensory Motor Integration
    21: The Visceral Motor System
    UNIT IV: The Changing Brain
    22: Early Brain Development
    23: Construction of Neural Circuits
    24: Modification of Neural Circuits as a Result of Experience
    25: Repair and Regeneration in the Nervous System
    UNIT V: Complex Brain Functions
    26: Association Cortex and Cognition
    27: Speech and Language
    28: Sleep and Wakefulness
    29: Emotions
    30: Sex, Sexuality, and the Brain
    31: Memory

Additional Resources

For Students

The Neuroscience Companion Website features review and study tools to help students master material presented in the neuroscience course. Access to the site is free of charge and requires no access code. The site includes:
- Chapter summaries
- An extensive collection of detailed animations
- Online quizzes
- Flashcards for every chapter

Sylvius: An Interactive Atlas and Visual Glossary of Human Anatomy

Sylvius provides a unique digital learning environment for exploring and understanding the structure of the human central nervous system. It features fully annotated surface views of the human brain, as well as interactive tools for dissecting the central nervous system and viewing fully annotated cross-sections of preserved specimens and living subjects imaged by magnetic resonance.

For Instructors

The Instructor's Resource Library for Neuroscience includes:
- Textbook figures and tables: all the figures and tables from the textbook, provided in JPEG format (both high- and low-resolution)
- PowerPoint presentations: all the figures and tables from each chapter, making it easy to add figures to your own presentations
- Animations: an extensive set of detailed animations
- Quiz questions: all of the quiz questions from the companion website
- Review questions: short-answer style review questions for each chapter