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Cover

Introduction to Glycobiology

Third Edition

Maureen E. Taylor and Kurt Drickamer

April 2011

ISBN: 9780199569113

304 pages
Paperback
246x189mm

In Stock

Price: £39.99

Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.

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Description

Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.

  • The only text to make this important area of biochemistry accessible to an undergraduate audience
  • Illustrates the biological importance of sugars with diverse examples, to stimulate and engage students throughout the biosciences
  • Thought-provoking questions linked to the latest research encourage the student to explore the subject for themselves, and gain an appreciation of how current research continues to push forward our understanding of the subject
  • The glycobiology of disease and the importance of sugars in the development of new therapeutic strategies are highlighted throughout
  • Online Resource Centre features additional resources for students and lecturers to enhance the educational value of the text

New to this edition

  • Updated content to reflect the current state of the field: new chapter on cell biology of glycosylation, expanded coverage of congenital disorders, proteoglycans, influenza virus, muscular dystrophy, and cancer
  • Marginal cross-references between the chemical first part and biological and biomedical second part of the book further emphasise the relevance of structure to function
  • New and updated special topic boxes represent the current research and applications of glycobiology to disease and therapeutics
  • Broadened treatment of analytical methods, including glycoarrays, provides an overview of the cutting edge techniques used to increase our understanding
  • New Journal Clubs feature discussion questions based on research papers and linked to topics featured in the book, to guide the process of assimilating knowledge from the research literature

About the Author(s)

Maureen E. Taylor, Imperial College London and Exeter College Oxford, and Kurt Drickamer, Imperial College London

Maureen Taylor is Senior Lecturer in Molecular Biosciences at Imperial College London and fellow and tutor in biochemistry at Exeter College, Oxford

Kurt Drickamer is Professor of Biochemistry in the Division of Molecular Biosciences at Imperial College London

Table of Contents

    Part 1: Structures and biosynthesis of glycans
    1: Concepts of glycobiology
    2: N-Linked glycosylation
    3: O-Linked glycosylation
    4: Glycolipids and membrane protein glycosylation
    5: Enzymology and cell biology of glycosylation
    6: Glycomics: analysis of glycan structures
    7: Conformations of oligosaccharides
    Part 2: Glycans in biology
    8: Effects of glycosylation on protein structure and function
    9: Carbohydrate recognition in cell adhesion and signalling
    10: Glycoprotein trafficking in cells and organisms
    11: Glycobiology of plants, bacteria, and viruses
    12: Glycobiology and development
    13: Glycosylation and disease
    14: The future of glycobiology

Reviews

Review from previous edition This book is an absolute must for all lecturers and students alike of glycobiology ... Wholeheartedly recommended. - Microbiology Today, November 2006

It covers the breadth of glycobiology very well and provides sufficient depth to provide a platform for further research. - Dr Gavin M. Brown, Lancaster University

Others are not written as clearly or concisely as Taylor and Drickamer. - Prof Y.C. Lee, John Hopkins University

I prefer this book highly above the other text books available. - Prof Dr J.P. Kamerling, Utrecht University

Dr Taylor and Professor Drickamer should be congratulated on writing a textbook that presents the enormous subject of glycobiology with energy and enthusiasm and doing so in a manner that should be accessible to their target audience. - Biochemist e-volution, April 2006